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Background: The study was designed to compare the effect of intraincisional vs intraperitoneal infiltration of levobupivacaine
0.25% on post-operative pain in laparoscopic cholecystectomy.
Materials and methods: This randomised controlled study was carried out on 189 patients who underwent laparoscopic
cholecystectomy. Group 1 was the control group and did not receive either intraperitoneal or intraincisional levobupivacaine.
Group 2 was assigned to receive local infiltration (intraincisional) of 20 ml solution of levobupivacaine 0.25%, while Group
3 received 20 ml solution of levobupivacaine 0.25% intraperitoneally. Post-operative pain was recorded for 24 hours postoperatively.
Results: Post-operative abdominal pain was significantly lower with intraincisional infiltration of levobupivacaine 0.25% in
group 2. This difference was reported from 30 minutes till 24 hours post-operatively. Right shoulder pain showed significantly
lower incidence in group 2 and group 3 compared to control group. Although statistically insignificant, shoulder pain was less
in group 3 than group 2.
Conclusion: Intraincisional infiltration of levobupivacaine is more effective than the intraperitoneal route in controlling postoperative
abdominal pain. It decreases the need for rescue analgesia.
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